Axon voltage-clamp simulations. I. Methods and tests
نویسندگان
چکیده
منابع مشابه
Nonuniform response in the squid axon membrana under voltage-clamp.
TASAKT, I. AND C. S. SPYROPOULOS. Nonunijorm response in the squid axon membrane under ‘voltage-clamp.’ Am. J. Physiol. 193(2): 309-317. 1958.-By cooling a portion of the squid giant axon at a time, it was shown that the repetitive membrane currents observed under the so-called voltageclamp conditions derived from the main portion of the ‘clamped’ axon membrane and not from the lateral unclampe...
متن کاملMembrane conductance and current-voltage relation in the squid axon under voltage-clamp.
,4BSTRACT TASAKI, I. AND C. S. SPYROPOULOS. Membrane conductance and currentvoltage relation in the squid axon under ‘voltage-clamp.’ &L-The conductance of the squid axon membrane under ‘voltage-clamp’ was measured by superposing a sinusoidal wave upon rectangular clamping voltage pulses. It was possible to determine the time course of the emf of the membrane under ‘voltage-clamp’ on a single p...
متن کاملCurrent-voltage relations in the isolated giant axon of the cockroach under voltage-clamp conditions.
Our understanding of the ionic exchanges taking place at the nerve membrane during electrical activity has been greatly increased by the application of the voltageclamp technique. This experimental method consists of the application of a stepwise change in potential to a given area of membrane and the simultaneous measurement of the current flow produced by this given potential gradient. The vo...
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The sucrose-gap method introduced by Stämpfli provides a means for the application of a voltage clamp to the lobster giant axon, which responds to a variety of different experimental procedures in ways quite similar to those reported for the squid axon and frog node. This is particularly true for the behavior of the peak initial current. However, the steady state current shows some differences....
متن کاملDiscrete threshold and repetitive responses in the squid axon under voltage-clamp.
TASAKI, I. AND A. F. BAK. Discrete threshold and repetitive responses in the squid axon under ‘voltage-claw@ By using the so-called voltage-clamp technique, records were obtained indicating the presence of undulatory or oscillatory membrane current under fixed potential difference between the internal and external electrodes. This oscillatory membrane current was observed only when rectangular ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1975
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(75)85788-2